Downloads / MSDS
Specification sheet and MSDS are available on request.
Description
| Catalogue Number | |
| Synonyms | NMP, 1-Methylpyrrolidin-2-one, 1-Methyl-2-pyrrolidon, N-Methylpyrrolidone, N-Methylpyrrolidinone, Cas 872-50-4 |
| Overview | N-Methyl-2-pyrrolidone (NMP) is a polar aprotic solvent commonly used in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS). It effectively dissolves both amino acids and coupling reagents, facilitating the activation and coupling of amino acid residues. Its high solvating power and stability make it ideal for promoting efficient peptide bond formation and resin swelling during synthesis. |
Product Information
| Formula | C5H9NO |
| Molar mass (M) | 99,133 g/mol |
| Density | 1.028 g/cm³ |
| Boiling point (bp) | ~202 °C |
| Flash point | 91 °C |
| Melting point | -24 °C |
Application(s)
Pharmaceutical Industry:
Solvent in solid-phase peptide synthesis (SPPS)
Reaction medium for drug formulation and active pharmaceutical ingredient (API) production
Electronics:
Used in the manufacture of lithium-ion batteries as a solvent for electrode binders
Employed in semiconductor cleaning and photoresist stripping
Polymers and Plastics:
Solvent for polyvinylidene fluoride (PVDF) and other high-performance polymers
Used in the production of polyimides and polyurethanes
Coatings and Paints:
Acts as a coalescing agent and solvent in paints, varnishes, and inks
Petrochemical and Chemical Processing:
Solvent in extraction processes, especially for aromatic hydrocarbons
Used in catalyst recovery and polymerization reactions
Agriculture:
Carrier solvent in some pesticide formulations due to its ability to dissolve both hydrophobic and hydrophilic substances
Cleaning and Degreasing:
Employed in industrial cleaners for removing resins, coatings, and adhesives
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